A Guide to Solid Phase Peptide Synthesis


Posted December 27, 2022 by henryjosephbio

If you want to learn about solid-phase peptide synthesis and get assistance from experts, contact the suppliers from a life science research support company and get access to custom peptides.

 
Most biological research requires peptides and proteins derived from α–amino acids for the control and regulatory mechanisms. Therefore, peptides play a significant role in organic chemistry, biochemistry, biotechnology and medicinal chemistry. Today researchers are greatly using peptides or derivatives of peptides for the production of various modern medicines that can help to cure serious health conditions and diseases. They are used as anti-cancer agents, antibiotics or drugs for controling blood pressure. That is why the demand for α–amino acids and peptides is notable in the research field. Solid-phase peptide synthesis is an automated synthesis method or technology that is basically used for the production of synthetic peptides.

As the demand for peptides is really high in the market, the automation of solid-phase peptide synthesis is highly appreciable. Also, different improvements have been made in peptide synthesis instrumentation to make synthetic peptides and their derivatives more available. It enables the scientific community and the biological industry to use sufficient peptides for research.

Synthetic peptides can be synthesized by using solid-phase peptide synthesis automatically. This process is used to produce epitope-specific antibodies, map antibody epitopes and study enzyme binding sites as well as design and synthesize novel peptide- or protein-mimetics or even whole enzymes.

Solid-phase peptide synthesis (SPPS) has different advantages that make it a better option over liquid-phase peptide synthesis (LPPS) for the production of large-scale synthetic peptides. If you are planning to get custom peptides through solid phase peptide synthesis process, check these advantages-

01. Excess reagents and products can be eliminated or washed away easily.
02. The use of excess reagents maximizes reaction rates.
03. Intermediates need no isolation or characterization.
04. Easy access to a vast range of solvents with low volatility and high polarity.
05. A ‘pseudo-dilute’ microenvironment can inhibit intermolecular reactions to ensure some modifications with ease.
06. Assurance of compatibility with automated synthesis technology

To learn more, browse the website of top life science research support companies or call the suppliers for more details.
For More Information : http://www.biobasic.com/peptides-splash-custom-peps/
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Categories Biotech
Tags solid phase peptide synthesis , peptide synthesis
Last Updated December 27, 2022