The global oligonucleotide synthesis market is anticipated to grow significantly i.e. 17.5% CAGR owing to increased adoption of synthesized oligos in therapeutic, diagnostic, and clinical applications, increased funding from the government, and rising emphasis for personalized medicine. In addition, the reducing cost of sequencing, and increased expenditure on genomics, and increased venture capital investment will accelerate the growth of the global oligonucleotide synthesis market.

The COVID-19 outbreak had a positive impact on the global oligonucleotide synthesis market as established pharmaceutical and biotechnology companies along with industry players of the global oligonucleotide synthesis market have contributed to producing oligo products to develop test kits, treatments, and vaccines to combat the infectious coronavirus disease. For instance, Bio-Synthesis Inc. has made ready-to-use cocktail assortments for example the SARS-CoV-2 N1 Oligo Mix, the SARS-CoV-2 N2 Oligo Mix, and the Human RNase P (RP) Oligo Mix for COVID-19 research.

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Based on the product, the synthesized oligonucleotides segment dominates the market owing to the wide adoption of synthesizers and consumables such as PCR primers have led to the increased share of synthesis products. Moreover, PCR technologies in the research and diagnostic field have a massive adoption owing to their cost-effectiveness, ease to use, and highly sensitive.

North America dominates the oligonucleotide synthesis market owing to the rising R&D activities in life sciences, increased emphasis on the safety & quality of healthcare, mounting demand for high-quality research tools for data reproducibility, and increased demand to develop personalized therapeutics. In addition, the presence of several industry players in this region and a strong foothold in genomics, proteomics, oncology, diagnostic screening, and drug discovery will further contribute to the growth of the oligonucleotide synthesis market.

There are growing opportunities in the Asia-Pacific region that will accelerate the growth of the oligonucleotide synthesis market. The demand is high in China, Japan, and Singapore. China is setting up a new facility for RNA oligonucleotide synthesis procedures. In addition, new approvals for oligonucleotide synthesis drugs particularly for spinal muscular diseases will augment the growth.

In 2021, Thermo Fisher Scientific has collaborated with the University of Sheffield to develop advanced end-to-end workflows for the characterization and monitoring of complex oligonucleotide and mRNA products.

The prominent players in the oligonucleotide synthesis industry include Merck KGaA, Agilent Technologies, LGC Biosearch Technologies, Eurofins Genomics, Eurogentec, GE Healthcare, Thermo Fisher Scientific, and Nitto Denko Avecia Inc.

Source: VynZ Research