Wound healing care is a major modern medical intervention. Chronic non-healing trauma or disease related wounds continue to cost annual healthcare budgets billions of dollars, recently estimated at US$25 billion in the USA alone. Surgical incision wound infections are the most expensive post-operative complication. Long term infection following prosthetic device implantation has also so far been an incurable problem and is on the rise. In addition, the problem of wound tissue scarring is itself a multi-billion dollar healthcare burden. Concurrently, tissue regeneration and repair has become a major field of research. Foreign, semi-artificial and autologous tissues are grown in the laboratory, intended for complex surgical integration into injured tissue sites, but not without major secondary infection and host rejection problems.

SILVER IONTOPHORESIS STIMULATOR (SIS) WOUND HEALING DEVICE

VIRAL INFECTION TREATMENTS ADVANCE:

Silver is the broadest spectrum antimicrobial substance known. The patent pending SIS silver-nylon cloth electrode and SIS machine system makes possible the most active, continuous and non-contact delivery of electrically generated silver ions to an already infected wound and for infection prevention. Additionally, the disadvantage of mechanical interference with granulation tissue formation at the critical beginning stage of surface wound healing from contact wound dressings, is also avoided.

NON-HEALING WOUND CARE ADVANCE:

The overriding role of the endogenous wound-generated electric field in driving and orchestrating surface wound healing has been known and studied extensively for decades. Until now, the reproduction of this major electro-physiological process has not been fully implemented outside of a research setting and into an integrated wound healing device. The flexible SIS silver-nylon cloth electrode positioning configuration has been developed specifically from extensive simulations of dynamic wound healing bioelectricity. The SIS machine is the world's first real-time, self-adaptive 'intelligent' Wound Healing Electro Stimulator Device that actively monitors, calculates and then supplements or replaces the overriding wound-generated electric field that leads wound healing. The SIS machine wound healing electro-stimulation is automatically and constantly scaled in real-time to the present bioelectric properties of the individual wound.

SCAR TISSUE REGENERATION TREATMENT ADVANCE:

The SIS machine and SIS electrode system completely and accurately fulfill the specifications of the only (patented) method ever documented of inducing in situ tissue healing and regeneration by means of direct cellular modification. Electrically generated silver ions, under the correct and individual wound-specific electro-stimulation parameters, trigger genetic de-differentiation of specific classes of cells present in the wound bed. These newly modified cells have been repeatedly shown to transform into a population of pluripotent 'stem cells', available to both remodel existing tissues and form completely new tissue during the Proliferative and Remodeling Phases of wound healing, not normally possible in the animal body.