Active B12 Test Market Overview

Active B12 Test Market size was valued at USD 227.24 Mn. in 2024 and the Active B12 Test revenue is expected to grow at a CAGR of 24.7% from 2025 to 2032, reaching nearly USD 1328.67 Mn. by 2032.

Vitamin B12 deficiency is increasingly common, especially among the elderly and individuals on vegetarian diets due to the vitamin’s primary presence in animal-based foods.Active B12 test Market, which determine the biologically active form of vitamin B12 in the bloodstream, are essential for diagnosing deficiencies that can lead to anaemia, fatigue, and neurological issues.

The global market is witnessing strong growth due to rising awareness of conditions like pernicious anaemia and folate deficiency. Lifestyle-related factors such as poor diet, smoking, and lack of exercise are contributing to increased cases, thereby driving demand for diagnostic testing.

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Market Dynamics

Drivers

Rising Incidence of B12 Deficiency: Increasing cases of B12-deficiency-related disorders, including macrocytic anaemia and folate deficiency, are key growth drivers.

Increased Awareness and Testing Demand: Consumer and clinical awareness of B12’s health impacts is enhancing demand for accurate diagnostics like the Active B12 test.

Restraints

Technical Complexity and Costs: Active B12 testing requires advanced equipment and trained personnel, limiting its adoption compared to total B12 tests.

Regulatory Challenges: High costs and long timelines for diagnostic test certifications across regions impede market expansion.

Slow Adoption in Clinical Practice: Limited support from medical societies and inconsistent guidelines slow down integration into routine diagnostics.

Segment Analysis

By Test Type

ELISA Assay: Dominated the market in 2024 due to high sensitivity, reliability, and global acceptance in clinical labs

Enzyme Immunoassay

Others

By Application

Folate Deficiency Anaemia

Pernicious Anaemia

Macrocytic Anaemia

Others

Regional Insights

North America led the market in 2024, driven by a robust healthcare infrastructure, high awareness of vitamin deficiencies, and strong presence of leading diagnostic companies. Europe and Asia Pacific are emerging as promising markets due to increased diagnostic awareness and rising patient populations.

Competitive Landscape

Recent Developments

March 2024: Axis-Shield Diagnostics acquired a biotech firm focused on vitamin deficiency diagnostics to enhance its product portfolio.

April 2024: Abbott introduced a new Active B12 Test Kit with advanced assay technology for improved clinical efficiency.

Key Players

Abbott

Siemens Healthcare Pvt. Ltd.

Roche

DiaSorin

Demeditec Diagnostics

Beckman Coulter, Inc.

Randox Laboratories Ltd.

Pathkind Diagnostics Pvt. Ltd.

LifeSpan BioSciences

Metropolis Healthcare Ltd.

Sussex Pathology Ltd.

Medichecks

Apollo 24 7

LalPathLabs.com

Testing.com

Blue Horizon Blood Tests

Lupin Diagnostics

Humankind Ventures Ltd.

Australian Clinical Labs

XX Inc.

Key Questions Answered

What is driving the Active B12 Test Market growth?
-Rising vitamin B12 deficiency across global populations.

What challenges does the market face?
-High testing costs, regulatory barriers, and slow clinical adoption.

What is the market size forecast?
-USD 1328.67 Mn by 2032 with a CAGR of 24.7% from 2025 to 2032.

Which segments are covered?
-Test Type (ELISA, Enzyme Immunoassay), Application (Anaemia Types), and Regions.

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