The report highlights trends prevailing in the market along with factors driving its growth. The growth of the cerebral aneurysm clips market is attributed to the increasing prevalence of brain aneurysm and associated risk factors and rise in research and development activities for treating cerebral aneurysms. However, the high cost of procedures hinders the overall market growth.

The List of Companies -
1. B. BRAUN MELSUNGEN AG
2. REBSTOCK INSTRUMENTS GMBH
3. KLS MARTIN GROUP
4. INTEGRA LIFESCIENCES CORPORATION
5. ORTHO-MEDICAL GMBH
6. MIZUHO AMERICA
7. ADEOR MEDICAL AG
8. PETER LAZIC GMBH

A brain aneurysm or cerebral aneurysm is the development of a bulge in the brain's blood vessels. The bulge puts pressure on the nerves or brain tissues, and rupture or burst can cause brain bleeding, which can be fatal to a patient. Factors such as genetic conditions, arteriovenous malformations, untreated high blood pressure, and smoking cause brain aneurysms.

The more established method of treating aneurysms is microsurgical clipping. The first aneurysm ever treated by surgical clipping was performed at Johns Hopkins Hospital by Dr Walter Dandy on March 23, 1937. During microsurgical clipping, a small metal clip is used to stop blood flow into the aneurysm. A craniotomy is performed to create an opening in the skull to reach the aneurysm in the brain. The clip is placed on the neck (opening) of the aneurysm to obstruct the flow of blood and remains inside the brain.

The growth of the cerebral aneurysm clips market is prominently attributed to the increasing prevalence of brain aneurysm cases worldwide. According to data published by the Brain Aneurysm Foundation in 2020, ~6.5 million people in the US, i.e., 1 in 50 persons, suffer from an unruptured brain aneurysm every year. Moreover, ~30,000 suffer a cerebral aneurysm rupture yearly, indicating that a cerebral aneurysm ruptures every 18 minutes. According to the Brain Aneurysm Foundation data, ~40.0% of ruptures are fatal and need intensive care and attention. According to studies conducted by the National Institutes of Health (NIH), ~3-5% of Americans might have an aneurysm in their lifetime. Per the National Library of Medicine information, 2022, the global prevalence of cerebral aneurysms is ~3.2%, with a mean age of 50 and an overall 1:1 gender ratio; this ratio changes significantly among the people of age 50 and above to reach 2:0, with the predominance of females. The rate of rupture causing subarachnoid hemorrhage (SAH) is ~10 per 100,000, which may be greater in Finnish and Japanese populations, among others.

Further, an increasing commonness of risk factors associated with cerebral aneurysms-smoking, insomnia, and high blood pressure-are anticipated to drive the market growth.

- According to a 2021 research study funded by the British Heart Foundation UK, smoking, insomnia, and high blood pressure are major risk factors for cranial aneurysm and aneurysmal SAH.

- According to the data published by the Centers for Disease Control and Prevention (CDC) in 2018, ~14 of 100 people in the US smoke cigarettes. Apart from smoking and tobacco consumption, hypertension is another prominent factor raising the prevalence of cerebral aneurysms. According to World Health Organization (WHO), in 2019, ~1.13 billion people worldwide suffered from hypertension.

- According to the research study titled "Estimating the Global Incidence of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review for Central Nervous System Vascular Lesions and Meta-Analysis of Ruptured Aneurysms," 2018, ~500,000 individuals in the world are likely to suffer from SAH each year, with almost two-thirds in low- and middle-income countries.

Various organic and inorganic strategies are adopted by companies operating in the cerebral aneurysm clips market. The organic strategies mainly include product launches and approvals. Further, inorganic growth strategies witnessed in the market are acquisitions, collaborations, and partnerships. These growth strategies allow the market players to expand their businesses and enhance their geographic presence, thereby contributing to the overall market growth. Further, acquisition and partnership strategies help them strengthen their customer base and expand their product portfolios. A few significant developments by key players in the cerebral aneurysm clips market are listed below.

TABLE OF CONTENTS
1. Introduction
1.1 Scope of the Study
1.2 Research Report Guidance
1.3 Market Segmentation
1.3.1 By Material Type
1.3.2 By Indication
1.3.3 By Condition
1.3.4 By End-User
1.3.5 By Geography
2. Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 North America PEST Analysis
4.2.2 Europe PEST Analysis
4.2.3 Asia Pacific PEST Analysis
4.2.4 Middle East And Africa PEST Analysis
4.2.5 South And Central America PEST Analysis
4.3 Experts Opinion
5. Key Market Dynamics
5.1 Market Drivers
5.1.1 Increasing Prevalence of Brain Aneurysm and Associated Risk Factors
5.1.2 Rise in Research and Development Activities for Treating Cerebral Aneurysms
5.2 Market Restraints
5.2.1 High Cost of Surgical Procedures
5.3 Market Opportunities
5.3.1 The surge in Geriatric Population
5.4 Future Trends
5.4.1 Growing Financial Aid for Innovation and Adoption of Surgical Robots
5.5 Impact Analysis
6. Global Analysis
6.1 Global Cerebral Aneurysm Clips Market Revenue Forecasts and Analysis
6.1.1 Overview
6.1.2 By Geography - Forecasts and Analysis
6.1.3 Market Potential Analysis, By Region
6.2 Company Analysis
6.2.1 Market Share Analysis, By Company
6.2.2 Market Positioning of Key Players
6.2.3 Comparative Company Analysis
6.3 Growth Strategy Analysis
6.3.1 Performance of Key Players
6.3.2 B. BRAUN MELSUNGEN A
6.3.3 MIZUHO MEDICAL Co. LTD
6.3.4 Peter Lazic GmbH
7. Analysis - By Material Type
8. By Indication
9. Analysis - By Condition
Continued.
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