Zinc plays an essential role in immune function, cellular growth, wound healing and metabolic processes. However, conventional zinc supplements can face challenges related to absorption and gastrointestinal tolerance. To address these formulation challenges, LipoEdge highlights an advanced liposomal zinc supplement developed by West Bengal Chemical Industries Limited (WBCIL), with scientific findings published in the World Journal of Pharmaceutical Science and Research.

The research explores how liposomal encapsulation can support zinc delivery through a phospholipid-based system. The formulation uses phosphatidylcholine as its lipid carrier, creating protective vesicles around zinc to improve its physicochemical properties and stability.

One of the most notable findings was an encapsulation efficiency of 94.51%, demonstrating effective zinc entrapment within the liposomal structure. Dynamic Light Scattering (DLS) analysis recorded an average particle size of 203.1 nm, while zeta potential measurements showed -40.79 mV. These parameters indicate favourable particle distribution and colloidal stability.

The six-month accelerated stability study further strengthens the research findings. When stored at 40°C ± 2°C and 75% ± 5% relative humidity, the formulation maintained encapsulation efficiency between 94.32% and 95%. Its zinc assay also remained almost unchanged, moving from 20.07% to 20.04%. Thermal testing at 105°C for four hours showed minimal changes, with encapsulation efficiency remaining around 94%.

The research also highlights several potential liposomal zinc benefits associated with advanced delivery technology. Zinc contributes to normal immune function, antioxidant defence, skin health and tissue repair. Liposomal encapsulation offers an alternative approach to zinc delivery, with potential applications in nutraceutical and pharmaceutical product development.

To validate the formulation, researchers used analytical techniques such as FTIR, DLS, SEM and EDAX. The SEM images revealed smooth, spherical liposomal structures, while the analytical results supported the formulation's structural integrity and effective zinc encapsulation.

These findings highlight the potential of advanced liposomal technology to address formulation challenges associated with conventional mineral supplementation. Further bioavailability and human studies will help establish its performance in different populations.

Through LipoEdge, this research showcases the role of scientifically characterised liposomal ingredients in the development of next-generation nutraceutical and pharmaceutical formulations.

Explore LipoEdge Liposomal Zinc: Discover the formulation and product specifications:

https://www.thelipoedge.com/product/liposomal-pharmaceuticals/liposomal-zinc/

Read the Published Scientific Journal: Explore the complete research and analytical findings:

https://www.thelipoedge.com/journals/?utm_source=chatgpt.com&utm_medium=social&utm_content=LipoEdge/magazine/LIPOEDGE#popup-journal-18

Short Scientific Reference: Gupta Banerjee P, Paul A, Chakraborty A, Kundu S. (2025). Liposomal Zinc Supplementation Formulated by WBCIL to Enhance Bioavailability and Therapeutic Potential in Health and Disease Management. World Journal of Pharmaceutical Science and Research, 4(3), 1418–1435. DOI: https://doi.org/10.5281/zenodo.15806571