Simply put, every square inch of a cleanroom should be absolutely pristine. Ceiling panels, lighting units, HEPA filtration units, sprinkler heads, walls, glass surfaces, process equipment, piping systems, floors, and manufacturing equipment must be decontaminated regularly. Perhaps the ambient air has to be monitored and maintained at proper levels. HEPA-filtered ventilation systems assisted by preventative measures help manufacturers limit airborne contamination. However, to be able to assure environmental purity, regular housecleaning procedures are essential.

Cleaning with both a HEPA-filtered vacuum and traditional wipe-down methods are standard housekeeping ways in most cleanrooms. Yet in critical cleaning situations, vacuuming is generally the more efficient method because particles are retained in the machine with little potential for being exhausted in to the atmosphere (provided your vacuum includes a HEPA-filtered exhaust stream). Vacuuming also eliminates the fiber particles that swabs and wipers may leave behind. Actually, measurements drawn in one cleanroom setting learned that a dusting system using disposable cloths polluted the area double as by using a HEPA-filtered vacuum.

Just what exactly but if your cleanroom vacuum include? First and foremost, any hoover utilized in a biotech parenteral cleanroom has to be HEPA-filtered in order that 99.97% of all particles into and including .3 microns are collected and retained. In addition, it is absolutely critical that the HEPA filter be installed following your motor to filter the exhaust stream. The motor%u2019s commutator and carbon brushes generate dust, and if the exhaust stream isn't filtered as opposed to dust will likely be released in to the environment.

Anything of caution: don't assume all HEPA-filtration systems are created equal. Make sure the vacuum you end up picking posesses a multi-stage, graduated filtration system for optimum operating efficiency. A graduated filtration system uses a series of progressively finer filters capture and retain particles since they proceed through the vacuum. The most important particles are captured first by coarser filters smaller particles will be caught and retained through the finer HEPA filters. This multi-stage system protects the HEPA filters from blockage and excessive wear-and-tear, maintaining peak performance. When equipped with an ULPA filter, it should retain up to 99.99% of most ultra-fine particles, down to and including .12 microns in size.

Additionally, the filtration with your vacuum should use oversized filters, which slow airflow throughout the larger surface area and optimize mid-air-to-cloth ratio. This permits the vacuum to only collect bulk of debris over extended amounts of time with minimal maintenance.

Besides owning an exceptional filtering system, any vacuum employed in a cleanroom ought to be a number of non-particle generating materials. For instance, non-porous, metal vacuums -equipped with smooth hoses and attachments -enable personnel to quickly wipe down and decontaminate equipment for faster, simpler sanitization and validation. And it ought to be specially packaged to prevent contaminates from entering the cleanroom environment when delivered.
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