Tylosin is an antibiotic that belongs to the class of macrolide antibiotics. It functions by binding to 50S ribosomal subunit and then interacts with 23S RNA thereby blocking aminoacyl-tRNA, which in turn inhibits protein synthesis. Tylosin is manufactured by fermentation of the bacterium— Streptomyces fradiae and is most effective against gram-positive bacteria compared to gram negative bacteria. The antibiotics is used to treat various infections in animals and respiratory infections in animals caused by Pasteurella multocida, Mannheimia haemolytica, and Haemophilus spp.


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According to a report by Canadian Food Inspection Agency, 2014, 11 concentrations of tylosin used for therapeutic purposes, range from 44 mg kg-1 to 110 mg kg-1 feed. Moreover, tylosin is used in pigs to treat porcine proliferative enteropathy caused by Lawsonia intracellularis — a Gram-negative bacterium. Agriculture grade Tylosin consists of 80-90% tylosin A, with smaller amounts of tylosin B, tylosin C, and tylosin D. Around 29% of the active tylosin can be recovered in fecal samples in animals that receive tylosin, orally.


Market Dynamics

The global Tylosin market is expected to witness significant growth over the forecast period, owing to rising demand for Tylosin in livestock industry. For instance, according to a study by Ministry for Primary Industries, New Zealand 2016, Tylosin accounted for over 83% of macrolide and lincosamide sales during 2011 and 2014 and the trend is expected to continue over the forecast period.

Moreover, certain mergers and acquisitions are expected to boost the market growth over the forecast period. For instance, Eily, Lilly, and Company acquired Novartis Animal Health in 2014. Varied product offering by manufacturers such as Elanco Animal Health is expected to propel the global Tylosin market growth over the forecast period. For instance, Elanco offers Component with Tylan, an implant line with initial and terminal implants for steers and heifers. This implant includes a tylosin tartrate (Tylan) pellet that dissolves and releases antibacterial throughout the implant site.

Continuous demand for tylosin in livestock industry is expected to propel growth of the global tylosin market over the forecast period

Antimicrobial medications are generally used in the livestock industry for treatment of various infections in the livestock, prevention of disease, and to improve growth rate of the animals efficiency. Moreover, antimicrobial medications have been found to be effective in animals for improving growth rate and increasing weight more efficiently, which in turn results in increasing profits for the meat producers.

According to National Center for Biotechnology Information (NCBI), 2015, around 80% of antibiotics sold in the U.S. are for animal agriculture and almost 70% of these are medically important (i.e. from classes’ important to human medicine). Moreover, according to NCBI, the antimicrobial consumption in livestock is expected to increase by 67% by 2030, and nearly double in Brazil, Russia, India, China, and South Africa. These factors are expected to boost the global Tylosin market growth over the forecast period.

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Key players operating in the global Tylosin market include Zoetis, Tairui Pharmaceuticals, Lukang Pharmaceutical, Henan Hualun, Qilu Pharmaceutical (Inner Mongolia) Co., Ltd, Huvepharma, AdvaCare Pharma, and Elanco Animal Health.


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